Pier Nicola Sergi

Dr.  Sergi , Pier Nicola

Telephone: 
+39 050 88 3059



Post Doctoral Fellow

About Me: 

EDUCATION

  • 2017 Application to Assistant Professor position at Scuola Superiore Sant'Anna. Assessment: Eligible
  • 2012 Master in “Bioethics and Teaching”, University of the Holy Heart and Pontifical Lateran University, Rome (I). (30/30 Summa cum laude). Discipline: Philosophy of Science. Thesis: “Science and scientism, a study of the epistemology of T. Kuhn and M. Polanyi” (Supervisor: Prof. Stephan Kampowski).
  • 2012 Application to Assistant Professor position at Scuola Superiore Sant'Anna.  Assessment: Eligible.
  • 2009 Philosophy Degree in Innovative Technologies, curriculum of Biorobotics, Scuola Superiore Sant’Anna (I), (100/100 Summa cum laude). Thesis: “Characterization of the peripheral nervous tissue biomechanics for the development of implantable neural interfaces”
  • 2006-2007 Visiting student at LPT (Theoretical Physics Laboratory), École Normale Supérieure, Paris, Cedex 05 (F)
  • 2005 Visiting student at the Biophysics and Neurophysiology department, Freiburg University (D).
  • 2005  Qualifying examination to Engineers Register, University of Pisa (I).
  • A.Y. 2004-05 Application to PhD student position in Biorobotics at Scuola Superiore Sant'Anna (I). Assessment: Winner
  • A.Y. 2004-05 Application to PhD student position in Robotics at Universty of Genoa (I). Assessment: Winner
  • A.Y. 2004-05 Application to PhD student position in Engineering of Microsystems at University of Tor Vergata Rome (I). Assessment: Eligible
  • A.Y. 2003-2004 Laurea Degree in Mechanical Engineering (106/110), University of Pisa (I)

 

LANGUAGES

English, French

Academic Writing and Academic Speaking courses at  CLI, University of Pisa (I)

AWARD

LaBS 2004 award, (Biologic structures laboratory, Polytechnic of Milan). Motivation: Best Master thesis on biomechanics. The award was given at XXIII National School of Bioengineering of GNB (Italian National Group of Bioengineering).

ATTENDANCE TO CONFEREES AND SUMMER SCHOOLS

  • 2014 Robosoft, Scuola Superiore Sant'Anna Pisa (I)
  • 2012 Neurobioetcs, Pontifical University Regina Apostolorum, Rome (I)
  • 2012 XVIII International Congress of the ESB, Lisbon (P)
  • 2011 Delegate of SSSA at the foundation of Italian Chapter of European Society of Biomechanics (ESB), Bologna (I)
  • 2011 XI International Conference on Computational Plasticity, Complas, [Invited by G. Holzapfel] University of Barcelona,  Barcelona (S)
  • 2010 Summer school on “Modelling in Biomechanics and mechanobiology at different length scales and computation in biomechanics” [coordinated by G. Holzapfel and R. Ogden ], University of Graz, Graz (AU)
  • 2008 Summer school on “Modelling and computation in biomechanics” [coordinated by G. Holzapfel and R. Ogden ], University of Graz, Graz (AU)
  • 2008 Italian National Congress of Bioengineering, Pisa (I)
  • 2007 NEUROBOTICS summer school, Volterra (I)
  • 2006 XXV Summer school of Italian National Bioengineering group, Brixen (I)
  • 2006 BIOROB 2006, “The first IEEE/RAS-EMBS International Conference on Biomedical Robotics and Mechatronichs”, Pisa (I)
  • 2005 XXIV Summer school of Italian National Bioengineering group, Brixen (I).

 

MENTORING

Current supervision of PhD student: Iolanda Morana Roccasalvo

A.Y.  2010-2011 "Computational model of neural growth on nanogratings", Master Degree Thesis in Bioengineering, University of Pisa (I).

Candidate: Iolanda Morana Roccasalvo.  Supervisors: Silvestro Micera, Cecilia Laschi, Pier Nicola Sergi. Mark 110/110 Summa Cum Laude
Winner of a GNB 2011 (Italian Group of Bioengineering) award (ex-aequo) for Neural Engineering, Biorobotics, Micro and Nano-technologies

A.Y. 2009-2010 "Design of a peripherical self opening neural interface", Master Degree Thesis in Bioengineering, University of Pisa (I)
Candidate: Annarita Cutrone.  Supervisors: Silvestro Micera, Paolo Dario, Silvia Bossi, Pier Nicola Sergi. Mark 110/110 Summa Cum Laude
Winner of a GNB 2010 (Italian Group of Bioengineering) award for modelling

 

TEACHING

From A.Y 2005-2006 to A.Y 2011-2013.  Basic course of Biomechanics, modulus of  Biomedical Technologies, Curriculum for hearing aid makers, Faculty of Medicine, University of Pisa (I).

 

PEER-REVEWER ACTIVITY

1 (Nature) Scientific Reports
2. PLOS ONE
3. Journal of Biomechanics
4. Journal of Neural Engineering
5. Journal of Physics D: Applied Physics
6. Journal of Micromechanics and Microengineering
7. Physical Biology
8. Nanotechnology
9. Inverse Problems
10. IEEE Transaction on Biomedical Engineering
11. ASME Journal of Computational and Nonlinear Dynamics
12. Measurement Science and Technology
13. Computational and Mathematical Methods in Medicine
14. Medical Engineering & Physics
15. PeerJ
16 IEEE Transactions on NanoBioscience
17 Food & Function
18 PLOS COMPUTATIONAL BIOLOGY
19 Materials Science and Engineering C
20 Biomedical Materials


 

 

SCIENTIFIC SOCIETIES MEMBERSHIP
(past and present)

  • ESB (European Society of Biomechanics)
  • EuroMech (European Society of Mechanics)
  • EMS (European Mathematical Society)
  • EPS (European Physical Society)

 

RESEARCH INTERESTS

Applied Physics; Applied Mathematics; Statistics; Solid mechanics; Theoretical, computational and applied biomechanics; Soft tissues biomechanics; Peripheral nerves biomechanics; Theoretical and applied biophysics; Modelling of biological and non-biological structures; Modelling of interactions between neural interfaces and biological tissues (e.g. nerves); Modelling of axonal outgrowth; Mathematical tools in structural mechanics and biomechanics; Interactions between solid (robotics) tools and soft tissues; Material science; Scientific issues related to nano and microtechnologies; Interaction between cells and micro/nano structured surfaces; Cytomechanics; Finite Element modelling; Scientific issues related to biorobotics; Plant Biomechanics and Biophysics; Biomimetics; Epistemology.

 

 


Selected Publications: 

 

Journal (submission/preparation)

(some papers)

Journal (published)

P.N. Sergi, E.A. Cavalcanti-Adam, Biomaterials and computation: a strategic alliance to investigate emergent responses of neural cells, Biomaterials Science 5 (4), 648-657, 2017

P. N. Sergi, W. Jensen, and K. Yoshida, Interactions among biotic and abiotic factors affect the reliability of tungsten microneedles puncturing in vitro and in vivo peripheral nerves: A hybrid computational approach. Materials Science and Engineering: C, 59:1089 – 1099, 2016

I.M. Roccasalvo*, S. Micera, P.N. Sergi*, A hybrid computational model to predict chemotactic guidance of growth cones, Sci. Report. 5 (2015), (*equal contributors), http://dx.doi.org/10.1038/srep11340

P.N. Sergi, A. Marino, G. Ciofani, Deterministic control of mean alignment and elongation of neuron-like cells by grating geometry: a computational approach, Integr.Biol. 7 (2015) 1242–1252, http://dx.doi.org/10.1039/C5IB00045


P.N. Sergi*, I. Morana Roccasalvo*, I. Tonazzini, M. Cecchini, S. Micera, Cell Guidance  on Nanogratings: a Computational Model of the Interplay between  PC12 Growth Cones and Nanostructures, PLOS ONE, 2013,  (*equal contributors). FREE DOWNLOAD AT: http://www.plosone.org/article/info:doi/10.1371/journal.pone.0070304

Sergi P.N., Jensen W., Micera S., Yoshida K., In vivo interactions between tungsten microneedles and peripheral nerves, Medical Engineering and Physics, Volume 34, Issue 6, July 2012, Pages 747-755.   FREE DOWNLOAD AT : http://arxiv.org/abs/1308.0525v1

Cutrone A., P.N. Sergi, S. Bossi , S. Micera. Modelization of a self-opening peripheral neural interface: a feasibility study, Med Eng Phys. 2011 Dec;33(10):1254-61.

Ciofani G.; Sergi P.N.; Carpaneto J.; Dario, P. & Micera, S. A hybrid approach for the control of axonal outgrowth, Medical and Biological Engineering and Computing, 2011, 49,2, 163-170.

Sergi, P. N..; Carrozza, M. C.; Dario, P. & Micera, S. Biomechanical characterization of needle piercing into peripheral nervous tissue. IEEE Trans Biomed Eng, 2006, 53, 2373-2386.

Abstracts on Conferences

Roccasalvo I., Sergi P.N.,  Cecchini M., Silvestro Micera S.,” Development of a computational framework for modelling the cell contact-guidance”, ENCODS 2013

Sergi P.N., Micera S., "Interactions between self penetrating neural interfaces and peripheral nerves", 11th. International Conference on Computational Plasticity - COMPLAS XI, 2011.

D. Accotoa, A. Benvenuto, A. Ghionzoli, P. N. Sergi, S. Bossi, S. Micera & E. Guglielmelli, Ex-vivo measurements of friction coefficient in porcine median nerve-polyimide contact Congresso Nazionale di Bioigegneria, 2010

P. N. Sergi, P. Dario, and S. Micera, "On the mechanical interaction between "needle-like" interfaces and the peripheral nervous tissue," presented at I Congresso Nazionale di Bioigegneria, 2008, 667-66.

Conference Proceedings

Sergi P.N. , Morana Roccasalvo I. ,Cecchini M. , Micera S., "Biomechanical coupling between PC12 and nanograting induces alignment of neurites", Journal of Biomechanics, Proceedings of ESB2012 - 18th Congress of the European Society of Biomechanics, 2012, 45, Supplement 1, S417

Sergi P.N., Micera S., "Interactions between self penetrating neural interfaces and peripheral nerves", 11th. International Conference on Computational Plasticity - COMPLAS XI, 2011.

Carpaneto J., Cutrone A., Bossi S., Sergi P.N., Citi L., Rigosa J., Rossini P.M., and Micera S.,"Activities on PNS neural interfaces for the control of hand prostheses", EMBS, 2011

Bossi S., Sergi P.N. and Micera S., ”Micromechanical model of a thin intrafacicular electrode during insertion into peripheral nerves”, Neural Engineering 2009, NER’09 4th International IEEE/EMBS conference on, 2009,100,103

Ciofani G., Sergi P.N., Carpaneto J., Raffa V., Menciassi A., Dario P., Navarro X., Micera S. On the control of axonal outgrowing for the development of new sieve interfaces. Proc. 10th International Conference on Rehabilitation Robotics, 525-530 (2007)

Ciofani, G.; Sergi, P.N.; Carpaneto, J.; Dario, P. & Micera, S. A hybrid approach for the control of axonal outgrowth Neural Engineering, 2007. CNE '07. 3rd International IEEE/EMBS Conference on, 2007, 81-84

Micera, S.; Sergi, P.N.; Zaccone, F.; Cappiello, G.; Carrozza, M.C.; Dario, P.; Guglielmelli, E.; Colombo, R.; Pisano, F. & Minuco, G. A low-cost biomechatronic system for the restoration and assessment of upper limb motor function in hemiparetic subjects Biomedical Robotics and Biomechatronics, 2006. BioRob2006 The First IEEE/RAS-EMBS International Conference on, 2006, 25-3

Micera, S.; Sergi, P.N.; Carpaneto, J.; Citi, L.; Bossi, S.; Koch, K.; Hoffmann, K.; Menciassi, A.; Yoshida, K. & Dario, P. Experiments on the development and use of a new generation of intra-neural electrodes to control robotic devices Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE, 2006, 2940-2943